Sunday, October 25, 2020

Exercise for the Prevention and Treatment of Parkinson's Disease


Parkinson’s Disease is a neurodegenerative disorder that afflicts almost one million Americans. It is characterized by the progressive loss of dopaminergic neurons which control movement. As Parkinson’s Disease progresses patients have progressive loss of the control of movement.

Symptoms generally develop slowly over years and can include:

Tremors, mainly at rest

Limb rigidity and stiffness

Walking and balance problems

In addition to these movement symptoms there are non-motor symptoms.   Non-motor symptoms include Hyposmia (loss of smell), sleep disorders, constipation, anxiety and depression.    These symptoms often affect patients more than their motor symptoms.

Exercise and Parkinson’s Disease

Exercise helps prevent Parkinson’s and slows the progression of the disease for those affected.   High levels of moderate to vigorous activities in mid or later life lower risk.    

Key parameters of exercise for Parkinson’s:

Task Intensity – higher is better meaning exercise must challenge the person.    

Task Specificity – the task must be specific to the motor circuits being affected – so using the area of the body affected is key.

Task Complexity – activity should be complex enough to engage the exerciser and require them to focus and engage.

To maximize benefit include activities that include an element of motor learning.   Introducing an element of skill development as part of an exercise program with activities such as dance or Tai Chi can be very beneficial. 

The Importance of Vigorous Aerobic Exercise

In addition to activities which challenge motor learning it is critical to engage in vigorous aerobic exercise.   This fits the overall requirement of engagement of the exerciser – more intense aerobic exercise requires more concentration and engagement!  Vigorous aerobic exercise is also shown to dramatically increase BDNF which is brain derived neurotrophic factor.   BDNF is like miracle grow for the brain – it is growth factor that is critical for maintaining synaptic connections and growing neurons.  Parkinson’s patients have decreased BDNF.

To learn more about exercise and Parkinson’s Disease check out this excellent interview with a leading Parkinson’s researcher:  https://www.foundmyfitness.com/episodes/giselle-petzinger

 






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